The traumatic events of recent years have resulted in Afghanistan becoming largely isolated from its neighbours. This process is now being reversed. One channel of interaction is Afghanistan's membership of regional organisations such as the Economic Cooperation Organisation, South-Asian Association for Regional Cooperation, Organisation of Islamic Cooperation, and Conference on Interaction and Confidence Building Measures in Asia. These bodies play a valuable role in re-integrating Afghanistan into the wider region, giving it visibility in regional debates and creating opportunities for collaboration in regional projects. A positive role is also being played by Afghanistan's neighbours and near neighbours. Some of these relationships are conducted on a bilateral basis, while others take place within multilateral structures. There is a high level of regional involvement in internationally-led initiatives. These include the fight against drug trafficking and other forms of organised crime, led by UNODC and affiliated institutions. Noteworthy, too, are the large-scale projects that are being implemented under the aegis of the Central Asia Regional Economic Cooperation (CAREC) programme, in particular CASA-1000 and the TAPI gas pipeline.