Pandemics occurred worldwide from at least 15.000 years, when a first organized human settlement was created in the Arabic peninsula. From then, systematically, epidemics have occurred periodically intensively shaping human behaviors, but also keeping moderate the population growth. Influenza viruses have been, and still today are, main protagonists of the pandemic recurrence. From thousand years up to day, seasonal flu epidemics have occurred each year all over the world. In a much longer interval completely new influenza viruses provoked massive pandemics leading to millions of deaths. Outbreak communication problems have always been an epidemic side effect: health authorities found themselves inadequate to effectively drive the population behaviors through the correct lines. The last Pandemic flu, 2009-10, also suffered intensively of communication problems, even in the actual era of fast real time communication. But the new web social networks sprouted all around the globe producing massive communication, thousand times more frequent than the Institutional communication. However this did not lead to a coordinated population action to better cope with the epidemic, but more to a wide information chaos that did not help the battle against the virus.