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V. Mesenchymal Stem Cells in Regenerative Medicine
Mary Murphy, Caroline Curtin, Garry Duffy, Claire Kavanagh, Timothy O'Brien, Frank Barry
51 - 61
10.3233/978-1-61499-076-5-51
Biomedical and Health Research
Volume 77: Regenerative Medicine and Cell Therapy
Abstract

Cellular therapy involves the isolation, expansion and transplantation of human cells for the replacement or regeneration of injured tissues. It is one of the most significant repair strategies in Regenerative Medicine today. Mesenchymal stem cells represent a versatile, multimodal cellular therapy for the treatment of a broad spectrum of diseases. They stimulate a host repair response by paracrine mechanisms involving immunomodulatory, cytoprotective and pro-angiogenic mechanisms. It also appears that they may be tolerated as a fully allogeneic therapy.

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