We position the HANDS project in the wider context of developments in mobile technology and consider what legacy the project leaves. We identify a series of overall conclusions and recommendations from the project about the ways in which “HANDS-like” technology, i.e. integrated suites of mobile apps designed to develop social and daily life skills in young people with autism spectrum disorders (ASD), should be developed and implemented in the future. We also set out a roadmap for a future research agenda, indicating further promising lines of enquiry that could potentially lead to the development of effective assistive mobile technology that has the potential to make a difference to the lives of young people with ASD and other people with social and cognitive impairments.