Warehouses are essential components of logistics and supply chains. The performance of warehouse operations significantly affects the efficiency of the whole chain it belongs to. Radio frequency identification (RFID) is an emerging technology capable of providing real-time information about the location and properties of tagged object(s), such as people, equipment or products. The main objective of this article is to provide some insights into the practical benefits that can be drawn from the RFID technology in the context of warehouse operations management. To this end, we have developed a set of heuristic routing and sequencing procedures that take, and, alternatively, do not take into account, real time RFID information and compared their performance via simulation on a set of randomly generated although realistic warehouse scenarios.