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Control of Tissue and Blood Optical Properties
Valery V. Tuchin
79 - 122
NATO Science Series, I: Life and Behavioural Sciences
Volume 369: Advances in Biophotonics
Abstract

This chapter aims to review the recent results on the optical clearing of the naturally turbid biological tissues and blood using the optical immersion technique. Basic principles of the technique, its advantages, limitations, and future are discussed. The refractive index matching concept for enhancement of in-depth light penetration into tissues and blood is discussed on the basis of in vitro and in vivo studies of optical clearing using optical spectroscopy, polarization and coherence-domain techniques.

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