In high-energy Pb-Pb collisions at LHC, a deconfined QCD medium is expected to be produced. The open charm and beauty mesons are a powerful probe to investigate the medium properties and its effects on particle production since they experience all the deconfined phase. The ALICE experiment is well suited to perform open-charm analysis thanks to the excellent tracking system, its high-resolution secondary vertex reconstruction capabilities and particle identification performance. In this proceeding the status of the analysis of p-p collisions at = 7 TeV and the perspectives for Pb-Pb measurements will be presented.