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There is a real potential for highly pathogenic and novel strains of pandemic influenza. In this chapter, new data on influenza and on the clinical and epidemiological characteristics of subtypes of viruses (H1N1)pdm09 and HPAI H5N1 are presented. Modern standards of organizing epidemiological surveillance on influenza, corresponding to International Health Regulations (2005) requirements across the pre-pandemic period, phases of pandemics, and post-pandemic period, are shown.
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