Nowadays most security relevant processes and workflows are statically defined and performed and hence all the necessary security measures must be determined in advance. Current research shows that the security level can be enhanced if these processes take into account real time risk information collected during their execution. We will present two application scenarios we developed for research projects: airport checkpoints with dynamically adapted security processes considering risk information from check-in luggage and passenger screening; and neutralization of improved explosive devices considering information from real-time risk mitigation. Both scenarios show that real-time risk mitigation and dynamically adapted workflows have the potential to enhance security and reduce risk. We will present basic conditions for the underlying information system infrastructure and the dynamic adaptation of the processes and workflows.