The paper presents participation of Polish Military Contingents (PMC) in multinational missions and military operations in the years 2003-2009 with special attention paid to Operation Enduring Freedom (OEF) in Iraq and International Security Assistance Force (ISAF) in Afghanistan. The volume, structure and dy-namics of the PMC’s combat losses in these operations are presented. Our own experience in treatment of 111 veterans with combat-related stress disorders is discussed. The paper also presents a summary of attempts in use of the Virtual Reality Assisted Exposure-Based Treatment for veterans suffering of PTSD as well as problems occurring in treatment and re-adaptation of PMC veterans after their return to Poland.