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This chapter offers an account of the work of the US National Academies, in cooperation with other national and international scientific organizations, to address increasing concerns about the potential security risks posed by continuing and dramatic developments in the life sciences. The work, begun in 2001, builds on a much longer line of work by the Academies on the periodic tensions between the culture of scientific openness and the desire to prevent adversaries from using advances in science and technology to cause harm to national or international security.
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