Development, construction and operation of buildings and structures are associated with disproportional consumption of energy, production of waste, emission of CO2 and transportation of materials. The first reason is the fragmented supply chain in the construction industry, that leads to sub-optimal buildings. The second reason is that buildings are built for long lifetime, where the world inside and around the buildings changes faster and faster. This also leads to suboptimal buildings. The third reason is that buildings are built as monoliths. All components are welded, poured, glued, sealed and cemented. This makes the building hard to change. These changes however are necessary to keep the building fit for use and up to date. The Living Building Concept is a business model for a more sustainable building industry. It is a business model which concentrates on the lifecycle of components and elements of buildings providing an economy of scale for innovative suppliers. Buildings can easily be kept up to date and fit for use with state of the art technology and in a sustainable way by changing parts and re-using the replaced parts in other buildings and structures. In that way buildings and structures show similarity with living organisms, changing slowly as a whole on the long term but changing fast and easy at cell level on short term. The characteristic “from cradle to grave” thinking of the construction sector then changes in a sustainable “cradle to cradle” thinking with substantial positive effects.