The rapid development of tissue engineering today allows us to envisage the clinical use of grafts of chondrocytes, autologous stem cells, biocartilage preparations or gene therapy . However, in spite of the high stakes for orthopedic surgery as well as rhumatology or sports medecine, the answers remain unclear. Clinical research on cell therapy and preparation of biocartilage must continue to be developed in order to better determine the choice of a support matrix (scaffold) the local mechanical forces on the cells (chondrocyte, MSL…).
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