The Tenth HealthGrid Conference and the Fourth International Workshop on Science Gateways for Life Sciences (IWSG-Life) offer a forum to discuss the integration of grid, cloud, and other e-infrastructures into the fields of biology, bioinformatics, biomedicine, and healthcare. The program includes presentations, demos, and tutorials on a wide range of topics from technologies to biomedical research, and from portals to workflow and computational modeling.

The principal objective of the HealthGrid conference is the exchange and debate of ideas, technologies, solutions, and requirements that interest the grid and life science communities and are likely to promote the integration of grids into biomedical research and health in the broadest sense. In 2012 the HealthGrid conference celebrates its tenth edition.

IWSG-Life is a workshop series that focuses on research contributions for science gateways and tools in the field of life sciences. It brings together scientists from the fields of life sciences, bioinformatics, and computer science. It therefore forms an international forum to exchange experience, formulate ideas, and catch up on technological advances in computational biology and chemistry in the context of science gateways.

The communities of both events overlap and in 2012 the events have been jointly organized such that attendees can benefit from synergies and will be stimulated to forge further links in their research areas. These proceedings record these events, their topics, and the peer reviewed papers and abstracts. Part I includes the contributions accepted to the HealthGrid conference in the form of oral paper presentations, tutorials, and demonstrations. Part II contains the papers about various aspects of the development and usage of science gateways for life sciences. The joint session is represented by Part III, which addresses the topic of science gateways for biomedical research.

We would like to thank the authors for their contributions and the committees for their efforts in organizing the events and reviewing the submissions. We would also like to express our gratitude to the local organizers; without their hard work it would not have been possible to make the events a success.

Not least we would like to acknowledge all our sponsors for their financial and/or media contributions. These are, in alphabetical order: AMC, BiG Grid, DANS, EGI.eu, IOS Press, iSGTW, NBIC, NICE, and SCI-BUS.

The Editors