The discovery of knowledge from raw data is a multistage process, that typical requires collaboration between experts from disparate disciplines, and the application of a range of methods tailored to the research question. The aim of the eLab is to provide a web-based environment for health professionals and researchers to access health datasets, share knowledge and expertise and to apply methods for analysis and visualization of the results. The eLab is built around the core concept of the Research Object as the mechanism for preserving, reusing and disseminating the knowledge discovery process. The possible range of applications of the eLab is vast, and so the consideration of the trade off between specificity and generality is an important one, that is reflected in the requirements. The architecture and implementation of the eLab is described, and we report on the deployment of eLabs for applications in primary care, long-term conditions management, bariatric surgery and public health.