New documentation and messages conforming to the rules of EDIFACT are created and an attempt is made to follow internationally standardised and wordwide available commercial experience. A set of medical documents, aligned with United Nations Layout Key for trade documents is designed. The approach is to develop a set of paper documents and to standardise the data which are filled in these documents. There is a possibility to fill the data directly in medical documents and to print them from the Clinical Information System in our University Hospital.