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In this study twelve L5-S1 disc necropsy samples aging from 28 weeks (stillborn foetus) to 84 years were examined by histological and immunohistochemical methods. The histological investigation was performed by light microscope (magnification *100, *250 and *400) and hematoxylin-eosin. The immunohistochemical examination inquired type III and VI collagen arrangement in lumbar disc. Notably, type III and type VI collagen organization in seven specimens aging from 28 weeks to 1 month , previously described by no Author, differed from that observed in adulthood and elderly life.
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