Until now many applications of knowledge based systems in medicine are technologydriven: some new computational or representational techniques are applied to a particular medical domain. But to get a usable system for the daily clinical routine there is an urgent need for an integrating methodology for medical knowledge based systems construction processes. Such a methodology must consider the organization of the clinical environment where it should run and the tasks in this organization which can profit from the knowledge based systems. The other important part is the interaction with other agents, various types of users (physicians, nurses, other healthcare professionals) and other software systems .
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