There is a widespread consensus that we have an urgent need to improve our workforce capacity in all aspects associated with the skills and knowledge required for successful e-health and health informatics developments, associated change management and systems implementation strategies. Such activities aim to support various health reform policy initiatives. This paper considers the work being undertaken by many researchers around the globe to define the range of skills and knowledge requirements to suit this purpose. A number of requirements and areas of specialisation are detailed. This is followed by descriptions for competencies in general and more specifically descriptions of a set of high level agreed Health Informatics competencies. Collectively these competencies provide a suitable framework useful for the formal recognition of Health Informatics, including e-health, as a nationally recognised study discipline. Nationally agreed competencies for this discipline enables all education and training efforts to be consistently implemented and to fit with the Australian Qualifications Framework covering both the Vocational Education and Training (VET) and Higher Education sectors.