Informatization has been bringing important, quick and extensive changes into the healthcare environment for years. Individual systems still represent isolated information islands; however, the need for interconnectivity and mutual accessibility has become more pronounced. On the one hand, integration of systems brings numerous, financially measurable advantages, and on the other hand, personal information in such systems becomes more vulnerable. Providing personal information protection is therefore the permanent task of informatisation and, with elimination of national borders and integration of national systems, it is becoming a challenge from the legal, organisational, technical and financial standpoints.