The “Foundations in Global e-Health” is a capacity building initiative designed for providers, managers, and ICT professionals in the healthcare sector. Currently being trialled through PANACeA (a pan-Asian e-health research network) it is intended to offer the course in other developing regions from 2011. Using adult education principles, this on-line, self-paced course is offered in a modular fashion comprising 12 modules; the workload of each module is in the range of 20-24 hrs, with modules 2 to 12 requiring 1 month for completion. The evidence-based curriculum is designed to provide an introduction to e-Health such that graduates of the program have a solid and standardised baseline awareness and understanding – a common foundation – from which they are better able to collaboratively communicate and independently develop and assess e-Health initiatives within their respective settings and countries.