In 2009 the Slovenian healthcare and health insurance sector is implementing a national system for the secure on-line exchange of administrative and medical data. All general practitioners, hospitals, pharmacies and other healthcare providers will connect their information systems to this electronic service. Solutions have been built upon, as well as the renovation of the existing well recognized national Health Insurance Card System. Using the On-line System, health professionals directly access centrally stored patient medical data (data on prescriptions issued, on medical technical aids, pregnancy, etc), and a comprehensive set of administrative data. The on-line system is a solid infrastructure for the further development of applications for direct data exchange between the information systems of healthcare providers. It has significant benefits for patients, healthcare professionals and health administration.