The purpose of this study was to evaluate the implementation of standardized physical and functional tests to individually monitor patients with a spinal cord injury (SCI) in 8 rehabilitation centers and to analyze enablers and barriers of the implementation process. A prospective effect- and process evaluation was performed. Team members responded to mailed questionnaires at the start (n=115) and end (n=82) of the one-year implementation period. Furthermore, a questionnaire was administered to managers (n=8), coordinators (n=8) and 32 persons with SCI in 4 centers. Outcome of the effect evaluation was the phase of implementation of standardized testing in each center. The process evaluation analyzed enablers and barriers of the implementation process. After a year of implementation, half of the centers shifted to higher implementation phases. None of the centers was classified in the highest phase. Enablers were the positive attitude of the team members regarding standardized testing and an encouraging local coordinator. Most important barrier was lack of time to implement standardized testing. It can be concluded that there is a large support for implementing standardized tests to monitor functioning of patients with SCI. During a year a positive shift was visible in the extent of implementation. Successful implementation of patient monitoring requires substantial amounts of time and effort of the rehabilitation centers involved.