The world is experiencing the popularization of mobile devices. This was made possible by the increasing technological advances and the advent of the Internet as a communication and information tool. These facts demonstrate that the development of applications compatible with such devices is an effective way to provide content to diverse audiences. In the educational field, these devices can be seen as technological support artifacts for distance education, serving as strategy for continuous and permanent education for health professionals. The Open University of Brazilian National Health System (UNA-SUS) offers distance learning courses, including specializating on free access. In order to increase the public reach, UNA-SUS developed mobile applications as supporting material for students. These applications can be accessed in offline mode, increasing the accessibility and therefore, improving the efficiency of the material. The 28 applications developed with responsive online books format currently reached the milestone of over 6,000 downloads. This number shows the positive acceptance of the format used, accentuated by the ease of having material downloaded from the device, not requiring the user to be connected to access content.