A pozzolan is a material that contains reactive silica or silica and alumina. When finely ground and mixed with lime in the presence of water, pozzolans react to form a cement-like product. Uganda has a vast potential for natural pozzolans especially in the rift valley areas. These can be used to produce a cheaper alternative material to Ordinary Portland Cement (OPC). However, limited investigations have been done in the past on their quality and potential to reduce the cost of housing especially for the low-income earners in Uganda. This study was aimed at generating data to determine their suitability for use in low-strength construction applications. The study established diverse physical and chemical properties of natural pozzolans in Uganda. The findings indicate a strong bearing between pozzolan grading and strength development. Due to the cost implications of attaining the finest grades, the ratio of pozzolan to lime in the blend was varied to attain optimum grades that can provide adequate strength for a number of low-strength construction applications without escalating the cost. The study recommends further investigation of strength variations of pozzolan-lime blends to generate products for specific applications at a reasonable cost.