As of today, analysis and design methods in aeronautical industry are based on simulations with a unique set of input data and model variables. But real operating conditions are a superposition of numerous uncertainties under which the industrial products operate, the presence of which is a major source of risk in the design decision process. The European project “NODESIM-CFD” (Non Deterministic Simulation for CFD Based Design Methodologies) – www.nodesim. eu – aims at providing tools able to evaluate and quantify uncertainties in aerodynamic and thermal performance predictions, thus contributing to support the goals of enhanced design confidence, risk reduction and improved safety.