In ultra safe and complex, dynamic systems, safety requires a new approach in which:

- safety is a strategic value in decision making and business modeling

- safety investigations focuses on knowledge deficiencies and systems change

- safety is a system state, represented by a state/space vector.

In order to cope with non-linear interactions and interventions, safety is designed into the systems as an inherent property before it manifests itself as an emergent property in practice. To this purpose, new scientific notions are mobilized, such as value and knowledge based engineering, forensic engineering and resilience management. The design of safer systems should apply a non-linear design methodology, including prototyping and simulation. Such design should focus on the functional level, inherent system properties and synchronization of event and system state vectors.