Large diameter bored piles currently represent a major element of deep foundations that can successfully be utilized in different subsurface conditions. However, there is an apparent difficulty in correlating the skin friction and end bearing resistances of such piles with the results of in-situ tests with adequate accuracy. Hence, the need for further research associated with the estimation of the ultimate capacity and load-settlement behavior of large diameter bored piles based on these tests is evident. This paper will focus on the assessment of skin friction of large diameter bored piles in cohesionless soil using correlation with in-situ tests such as standard penetration test (SPT). Traditionally, average SPT blow counts have been used, which invariably involves various degrees of uncertainty. This uncertainty can be attributed to several factors, such as soil spatial variability, effect of construction technique, and model uncertainty. Engineering judgment and reliance on appropriate factors of safety have been the conventional tools adopted in the geotechnical engineering practice to deal with the uncertainty associated with pile design. There is a need, however, to develop theoretically-sound methods to account for the uncertainty in SPT-based pile design especially for large diameter bored piles where pile settlement becomes of significant importance. In this paper, an attempt is made to develop a new SPT-based correlation with the maximum skin friction capacity of large diameter bored piles, in sand, that takes into account the effect of various sources of uncertainty.