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Drug Therapy in Older Persons
Barry Cusack, James Branahl
203 - 224
Drug Benefits and Risks
Abstract

Drug use in older patients generally is similar to that in younger adults. There are however, unique challenges that make drug use more complicated in the older population. These include altered physiology that can change pharmacokinetics and drug sensitivity with age. In addition, multiple diseases are common in older patients and this leads to multiple drug therapy. In turn the risk of drug–drug interactions and drug–disease interactions increase with age. These problems are discussed in this chapter in addition to discussion of therapeutics of important disorders in the older population.

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