Color Doppler and intravenous angiography (digital technique) can widely be used in experimental medicine. Their wide clinical application, availability, simplicity and small cost impose their importance. Color Doppler analysis of the vascular activity of certain region is more precise than the classic intravenous angiography, but requires contact of highly sophisticated equipment with the experimental animal. Intravenous angiography gives somewhat rougher image, but is more available and does not require the potentially unwanted contact. In this research, we used both methods to mark the vein bypass of the modified infrahyoid lobe dissected from the dog (used as experimental animal). We marked the horizontally placed vein bypass at the level of the thong bone using Color Doppler and intravenous angiography. Applied vein bypass performed the vein drainage of the modified infrahyoid lobe. Results obtained with these two diagnostic methods were compared with the pathohistological (PH) analysis. Results obtained using Color Doppler (using the probe GE Vivid 3 frequency of 5 to 12 MHz) were somewhat closer to the results of PH analysis which we consider as the most objective. Result obtained using intravenous angiography (digital technique using the Siemens Siregraph machine) were satisfactory in marking the required blood vessel for the experiment. Color Doppler and intravenous angiography as digital diagnostic procedures in experimental surgery are usable and as such significantly objective, widely available and do not require additional financial investments.