This paper examines the concept and practice of dehumanization, as well as potential new developments and implications for this concept that arise with the increasing use of machines, or more broadly, autonomous systems in our life. In recent times, philosophy has shifted its focus towards investigating wrongdoings, particularly the occurrence of dehumanization, rather than pursuing ideal theory. Dehumanization refers to the perception of others as less than fully human by denying them certain uniquely human characteristics or their human essence. Previous analyses of dehumanization have focused on events involving multiple human individuals, such as genocides, civil wars, and violence against certain ethnic, racial groups or women. However, it is still necessary to address new profiles of dehumanizing behaviors in the specific human-machine relationship.