This study evaluates the usability of a Therapy and Monitoring System (TMS) designed to enhance interdisciplinary collaboration in acute geriatric wards. Developed through an iterative co-creation process with end-users, TMS integrates features such as profession-specific views, geriatric assessment tools, and electronic health record (EHR) integration. Using the System Usability Scale (SUS), data were collected from 53 participants across three hospitals in Austria, representing professions such as nursing, medicine, psychology, and occupational therapy. The overall mean SUS score was 69.2 (SD 14.5), indicating moderate usability, with notable differences between professions. Nurses and medical doctors reported lower usability scores compared to psychologists and occupational therapists. Qualitative findings highlighted benefits such as improved interdisciplinary collaboration and documentation efficiency, alongside challenges like double documentation and technical limitations. These insights provide a basis for refining TMS to better support multi-professional workflows, with future iterations focusing on addressing integration barriers and user feedback.