Prostate cancer is a slow-growing cancer whose incidence increases with age. IL-6 expression is significantly increased in a variety of malignant tumor stroma, which is a key factor involved in the association between inflammation and tumor. So as to investigate how prostate cancer works, recombinant IL-6 was used to stimulate human prostate cancer cells (PC-3). After treatment for 24,48,72h, the viability of cancer cells was detected by CCK-8 experiment. The effect of recombinant IL-6 on the invasion of prostate cancer cells was analyzed by Transwell experiment. The results showed that IL-6 can increase the viability of prostate cancer cells and facilitate the invasion of prostate cancer cells.