Nonalcoholic fatty liver disease (NAFLD) is a clinical syndrome, and pathologically characterized by diffuse macro-vesicular fatty change in the hepatocytes. NAFLD includes simple nonalcoholic fatty liver disease, nonalcoholic steatohepatitis (NASH) and hepatic cirrhosis. NASH is a disease evolving under the influence of various stimuli still poorly understood, but where insulin resistance is prominently. In this paper, we present a new diagnosis model to predict NASH.