Evaluation criteria for health information systems (HIS) and health information technologies (HIT) is broad, diverse and lacks a gold standard approach that could be leveraged, to evaluate clinical systems at various stages of their system development life cycle (SDLC). Without generalizable tools such as frameworks or models, comparative analysis across HIS and HIT is not possible. This paper presents the findings from a scoping review, utilizing the Arksey and O’Malley methodology [1]. The objective of this review is two-fold: 1) to classify models and frameworks published between the years 2010–2020 according to their level of evaluative focus (e.g. micro, meso, macro, multi), 2) to identify the countries where these models and frameworks have been employed for the purpose of evaluation, using the International Medical Informatics Association (IMIA) Represented Regions [3]. The results demonstrated the heterogeneity of evaluation models and frameworks currently used in health informatics and reflected the necessity for more adaptive approaches to HIS and HIT evaluation.