With the development of society, people’s concern for the environment is increasing, and sustainable design permeates every aspect of life. The combination of science and technology, and the intersection of technology and nature have promoted the development of digital bionic technology as an important means of sustainable development. This paper explores the emerging concept of digital bionic design and its potential application in the field of sustainable interior space design, and introduces the theory of digital bionic design by collecting literature and inquiring about cases, and the specific application of combining it with interior design, so as to achieve the creation of a space that is optimized for functionality, aesthetics, and ecology, and to satisfy the natural emotional needs of the user’s outputs with the beautiful visions of environmental protection and resource sustainability.