In order to improve the engineering application performance of artificial-sand concrete, C30 concrete is used as the sample in this paper, and studies the performances of machine-made sand concrete under ordinary mixer and vibratory mixer through comparative tests. Under the same mixing ratio, the artificial-sand completely replaces the common river sand. The test results show that the slump, expansion and air content of the sand concrete made by the vibratory mixer increase compared with the ordinary mixing. The slump deviation coefficient and evacuation time deviation coefficient of concrete under vibratory mixing are reduced, and the workability of artificial-sand concrete of vibratory mixer is more stable. The 7 day and 28 day compressive strength of artificial-sand concrete by vibrating mixer is 9.3% and 14.8% higher than that of artificial-sand concrete by ordinary mixer, respectively, and the coefficient of variation is smaller. The results show that vibratory mixing is an excellent process that inhance the compressive strength of artificial-sand concrete, which has engineering application value.