Based on a project in Lanzhou City, in view of the limitations of traditional construction technology, combined with the actual project, the innovative use of “subway tunnel supporting pile + steel reinforced concrete column, beam and slab structure overall installation technology” has solved the problem of internal force loss of the pre-support steel structure, the problem of concrete cutting, pouring and pile quality when the subway tunnel supporting pile has a large pile distance and is constructed at both ends at the same time. Finally, the mechanical performance, overall performance, stability and other technical indicators of the whole supporting system meet the requirements. It not only ensures the stability of the foundation of the new building, but also provides advance support for the excavation of the subway line 4 tunnel in the future. The technology is mature, the method is reasonable, the measure is effective, after each technical examination and Recheck, the settlement of subsequent building construction is stable, the support system achieves the design each target request.