Based on the rapid development of 3D reconstruction technology and its expanding application in the direction of medical images, this paper proposed a research direction of 3D reconstruction of part of digestive tract based on single wireless capsule endoscope image by referring to Pixel2Mesh network. Experiments were carried out on the Data set of Kvasir-Capsule, and the results showed that compared with previous studies, the 3D model realized in this paper was more three-dimensional. At the same time, this paper provides a new idea for the development of 3D reconstruction technology in the direction of wireless capsule endoscope images.