Evaluation of the vibration reduction of piled-slab is of great significance for the layout of process and power equipment in high-tech facilities. In-situ measurement was performed to study the vibration reduction of the piled-slab of a high-tech lab. Slab vibrations with frequencies of 10 Hz to 60 Hz with steps 5 Hz were induced by an electromagnetic vibration exciter. INV3062U data acquisition device and 941B sensor were used to measure the velocities in the vertical direction at six measurement locations on the slab surface. For single frequency, the measurement results showed that the peak values of the slab vibration velocities generally decayed nonlinearly as the distance increased, however, the attenuations of 25 Hz, 35 Hz, 40 Hz, 50 Hz and 60 Hz slab vibrations were not monotonically.