In the architectural planning and design, the commonly used architectural layout forms are determinant, diagonal, etc. Because of its centralized and symmetrical layout form, determinant architecture has been widely used in urban architectural design. Due to the high density of multi span buildings, the ventilation effect is not good, so this paper mainly studies the influence of multi span building layout on the wind field of urban ordinary residence. In order to optimize the wind environment of the building, a 7-story residential area was modeled and calculated by CFD. Through the analysis of wind field characteristics at different building heights, the results show that the total wind speed in Z direction of the building is the smallest, about 3.354 m/s; At the same time, the overall wind pressure values are within 5Pa of the standard wind pressure difference, but we still need to pay close attention to the possible environmental impact at the outlet of the determinant residence.