The water landscape in college and university is the research object in this article. Through on-site investigation, monitoring and computer simulation in campus, combined with qualitative and quantitative research methods, the advantages and disadvantages of the spatial layout of the water landscape in campus are compared. In addition, the surrounding building layout and greening layout are aslo separately studied in this article. The research results show the influence mechanism of the water landscape and its spatial layout on the ecological health effect, providing a reference experience and basis for the campus ecological landscape planning.