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The Action Research aimed to develop of Quality Assurances System for Medical Laboratory in the Primary Care Units (PCUs), Roi Et province, Thailand. Data were collected by a questionnaire, in-depth interviews within a participatory process, employing both descriptive statistics, and inferential statistics. The results revealed that the process for the system included 7 steps: 1) Situation analysis, 2) Analyze and evaluate the situations, 3) Making a plan, 4) Action within planning, 5) Observation, 6) Reflection, and 7) Evaluation and implementation. The results also concluded consisted of 4 main activities: 1) Internal Quality Control 2) Intra-facilitator and support 3) Informal Quality Assessment and 4) Participatory System Evaluation. Recommendations of the study were included the model as of the main local policies, and create and encourage quality concept as the positive attitudes for staff and generate quality of working culture among the PCUs team.
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