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Electronic prescribing, defined as the electronic generation and transmission of a medication order for community-dwelling patients, is presented as an essential technology to improve medication use. The objective of this study was to evaluate a nationwide e-prescribing system in Quebec, Canada. A mixed-method study was conducted from July 2017 until June 2018. A descriptive analysis of e-prescription usage was performed using aggregated usage data, combined with an exploratory descriptive analysis of the e-prescribing system from the perspective of users of two electronic health records (EHR) and pharmacy management systems (PMS) (n=9 prescribers; 8 pharmacy technicians and 11 pharmacists). Overall, the adoption of the system was low, with only 2% of prescriptions being electronically transmitted and retrieved during the study period. Alignment problems were identified on the prescriber’s and receiver’s side, generating safety issues, and hindering the potential for benefits realization.
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