Developed at the North Carolina State University College of Design in the 1980s, a group of architects, product designers, engineers, authors and environmental design researchers, collaborated to establish the Principles of Universal Design to guide a wide range of design disciplines including environments, products, and communications [1]. Universal Design for Learning (UDL) is a research-based set of principles intended to guide the design of learning environments that are accessible and effective for all. First articulated by CAST (Center for Applied Science and Technology) in the 1990s and now the leading framework in an international reform movement, UDL informs all of our work in educational research and development, capacity building, and professional learning. UDL is based on cognitive neuroscience and is intended to guide the development of flexible learning environments that can accommodate individual learning differences [2]. UDL asks educators to create curricula that provide: multiple means of representation, multiple means of expression and multiple means of engagement, while motivating all students to learn and succeed [3]. Greensboro College is unique in higher education in that it has committed to fully embracing UDL. Greensboro College uses UDL as a framework for successful academic and student development at a small, private, Methodist-affiliated, liberal arts college. Greensboro College has initiated its transformation to an institution that values and facilitates UDL across its curriculum. As The Mission Statement of Greensboro College points out, we as a college believe “Universal Design for Learning, at its core is a comprehensive educational framework that removes barriers to student learning and academic success. The principles of UDL recognize that variance in learning ability and style among individuals is the norm and not the exception. Therefore, curricula should be adaptable to individual learning differences rather than the other way around” [4]. Greensboro College has taken its first steps towards providing a learning environment for all students, which can be used as a model for launching a UDL initiative at a small, liberal arts, private college [5].