The aim of this study is to describe the implementation and evaluation of an outsourced Clinical Decision Support Systems (CDSS) service of drug-drug interaction (DDI) alerts in an Uruguayan outpatient healthcare network. A cross-sectional study was developed. 1.5 alerts were triggered of every 1000 prescriptions. Clinicians accepted 44% of the total alerts. In conclusion, the implementation of CDSS was achievable.
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