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Technical Challenges and Opportunities when Implementing Pharmacogenomics Decision Support Integrated in the Electronic Health Record
Pedro J. Caraballo, Joseph A. Sutton, Ann M. Moyer, David Blair, Lois C. Hines, Padma S. Rao, Mark F. Adams, Sahana Murthy, Tina Garza, Mary E. Karow, Harmanjit Singh, Jyothsna Giri, Donald B. Gabrielson, Jennifer St. Sauver, Suzette J. Bielinski, Mark A. Parkulo
Clinical use of pharmacogenomic (PGx) knowledge at the bedside is new and complex. Our program has implemented multiple PGx-CDS interventions in different clinical settings and in multiple commercial EHRs. Herein, we discuss lessons learned and propose general technical guidelines related to PGx implementation.