With the rapid development of medical information systems in Chinese hospitals over the last two decades, many of these organizations have accumulated astronomical amounts of structured and unstructured clinical data, including patient diagnostic data, treatment data, lab test data, etc. Secondary use of these data for research, such as Real World Evidence (RWE) studies, has the potential to improve medical quality and safety in daily clinical practice. In this study, we describe CaseBase, a Clinical Data Warehouse (CDW) that extracts structured clinical symptoms or findings and related temporal information from narrative clinical documents and integrates medication information from the CPOE system. An Adverse Drug Event (ADE) signals detection platform has also been developed based on CaseBase to analyze and visualize drug-symptom relations in clinical data. A prototype of this platform has been evaluated in a 2,000-bed hospital and some initial results are reported here.
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
Tel.: +1 703 830 6300
Fax: +1 703 830 2300 firstname.lastname@example.org
(Corporate matters and books only) IOS Press c/o Accucoms US, Inc.
For North America Sales and Customer Service
West Point Commons
Lansdale PA 19446
Tel.: +1 866 855 8967
Fax: +1 215 660 5042 email@example.com