Background: TranSMART has become an important and widely used platform for the translational research. Included features for analysing data have significant deficiencies concerning user interactivity with and export of the generated results. SmartR, a plugin for tranSMART, promises to close this gap with its interactive workflows.

Objectives: Test with a proof of concept whether an own SmartR workflow is possible. Improvement of the integrated survival analysis with a self-build workflow, taking specific user requirements into account.

Methods: Analysis of existing SmartR workflows to understand the underlying SmartR architecture. Implementation of a SmartR workflow, which provides an improved survival analysis.

Results: Extension of SmartR and thus tranSMART is possible and could be successfully achieved with a prototype for survival analysis. The framework still lacks some functionality, like binning of continuous variables, and documentation.

Conclusion: SmartR workflows are a good way for realising interactive analysis, but the SmartR framework still needs further improvements to become a full alternative to the already existing Rmodules.