This paper describes the application of a transdisciplinary process oriented framework named Transdisciplinary Process Science and Technology, which employs the key concepts and techniques from diverse disciplines that deal with complex discrete event processes - namely Model Based System Engineering, Project Management, Business Process Management, and Simulation – as a base for the creation and implementation of generic Product Lifecycle Management supporting systems for use by Small and Medium Enterprises. The friendly and affordable applications created can be put to work together in a Product Lifecycle Management generic environment that is used to support the automated execution and management of the essential procedures in the development of short lifecycle engineering projects, as an alternative to complete and/or tailored Product Lifecycle Management and Business Process Management systems, which are usually costly, complex, difficult to customize and to integrate with the other organisations's legacy software applications.